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Acceptable Daily Intake

Specification and Aims of ADI

Unlike the PDE (Permissible Daily Exposure), the ADI considers oral intake only, and might therefore be the better choice for oral-only health products or food related products.


Indicate Toxicity

The ADI concept can be understood as a measure to indicate the toxicity of long-term exposure to repeated ingestion of chemical compounds (present and/or added), as opposed to acute toxicity.

Determination of NOAEL

The No-Observed-Adverse-Effect Level, the amount of a substance that shows no toxic effects, is determined by performing studies with several doses including high doses. In several studies on different effects, the lowest NOAEL is usually taken.

Safety and Quality

The determination of an ADI is to verify the safety of an (orally administrable) compound and the provision of high quality pharmaceutical products.

IASON consulting is the partner of choice for the determination of ADI and NOAEL

As one of the most successful health science consultation providers on the market, our team of consultants has the experience and know-how to provide quick, reliable, and specific services with regard to ADI or NOAEL determination as well as any other pharmaceutical and/or biotechnological request. Please feel free to contact us to find out more about IASON consulting and our provided services throughout the health care industry at any given time.